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Medchemexpress LLC 4-p-pdot | 134865-74-0 | MFCD00901545 | >98.0% | 279.38 g/mol | C19H21NO | 25 MG

Supplier: Medchemexpress LLC HY10060925MG
4-P-PDOT is a potent, selective melatonin MT2 receptor antagonist used in research to probe melatonin signaling and antioxidant pathways. It exhibits strong selectivity for the MT2 subtype and has been reported to counteract melatonin-mediated antioxidant responses such as changes in GSH/GSSG ratio and Nrf2 activity.
- Potent, selective MT2 receptor antagonist.
- Greater than 300-fold selectivity for MT2 versus MT1.
- Useful for studies of melatonin-mediated antioxidant signaling.
- Modulates GSH/GSSG ratio, phospho-ERK, and Nrf2 activity.
- Available as an analytical standard for research use.
- High purity (≥98%) suitable for biochemical assays.
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