Medchemexpress LLC 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-, hydrate (1:x) | 853645-22-4 | 99.8% | 247.14 | 5 G

Supplier:  Medchemexpress LLC HYW0117275G

Pyridoxal 5'-phosphate hydrate is the active form of vitamin B6, serving as an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase, which is involved in producing neurotransmitters like dopamine and serotonin. It is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and can be interconverted with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).

• Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression in HepG2 cells.
• Inhibits the proliferation of cancer cells SK-OV-3 and OVCAR-3.
• Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
• Inhibits the formation of advanced glycation end-products (AGEs) and prevents the progression of diabetic nephropathy in Streptozotocin-induced rat diabetes models.

Catalog No. 50-004-52327