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Apexbio Technology LLC 4-Thiouridine(Synonyms: 4-Thio-uridine, 4SU, s4U, 4-thiouracil riboside, 4-thio-ribouridine), 100mg, CAS: 13957-31-8.
Supplier: Apexbio Technology LLC C3722100
4-Thiouridine (CAS 13957-31-8) is a thiol-substituted ribonucleoside analog commonly utilized in RNA research for photoactivatable labeling and RNA cross-linking experiments Structurally 4-thiouridine differs from natural uridine solely by the substitution of a sulfur atom at the 4-position of the nucleotide base Due to this close structural similarity it integrates into RNA sequences with minimal disruption preserving typical base-pairing properties and RNA functionality Upon UV irradiation the incorporated thiol group induces covalent short-range RNA RNA cross-links facilitating detailed analysis of RNA interactions turnover rates and dynamics within cellular contexts
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