4-Trifluoromethyl-1H-pyrazole, 97%

Description

CAS: 52222-73-8 | C4H3F3N2 | 136.077 g/mol

It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.

Notes
Incompatible with strong oxidizing agents. Store at room temperature.

Specifications

Chemical Identifiers

• CAS: 52222-73-8
• Molecular Formula: C4H3F3N2
• Molecular Weight (g/mol): 136.077
• MDL Number: MFCD11226572
• InChI Key: KDEJQUNODYXYBJ-UHFFFAOYSA-N
• Synonym: 4-trifluoromethyl-1h-pyrazole, 1h-pyrazole, 4-trifluoromethyl, 4-trifluoromethylpyrazole, 4-trifluoromethyl pyrazole, 4-trifluoromethyl-1 h-pyrazole, 4-trifluoromethyl ;-1h-pyrazole
• PubChem CID: 12777795
• IUPAC Name: 4-(trifluoromethyl)-1H-pyrazole
• SMILES: C1=C(C=NN1)C(F)(F)F

• Melting Point: 76°C to 78°C
• Quantity: 1 g
• Formula Weight: 136.1
• Percent Purity: 97%
• Chemical Name or Material: 4-Trifluoromethyl-1H-pyrazole

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only