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Medchemexpress LLC 4-Vinylphenol | 2628-17-3 | 120.15 | 1 ML
Supplier: Medchemexpress LLC HYW00528810MM/1ML
4-Vinylphenol is a compound found in the medicinal herb Hedyotis diffusa Willd and wild rice. It is also a metabolite of p-coumaric and ferulic acid produced by lactic acid bacteria in wine. This compound induces apoptosis, inhibits blood vessel formation, and suppresses invasive breast tumor growth in vivo.
- Significantly reduces cell viability in parental MDA-MB-231 cells, with an IC50 value of 109 μg/mL.
- Reduces sphere formation and vimentin expression on CSCs in breast cancer.
- Significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells.
- Significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells.
- Significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis.
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