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ABclonal Technology 450 Rat anti-/Human CD45R/B220

Supplier: ABclonal Technology A27783100UG
This gene encodes a protein with tyrosine phosphatase activity and the ability to bind heparan sulfate and heparin It plays roles in lymphocyte differentiation signal transduction regulation and macromolecule metabolism The protein is located on the external side of the plasma membrane in focal adhesions and membrane rafts It is expressed in various tissues including the hemolymphoid system placenta and cardiovascular system It is studied in the context of systemic lupus erythematosus Its human ortholog PTPRC (CD45) is linked to hepatitis C multiple sclerosis and severe combined immunodeficiency
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