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ABclonal Technology 488 Rabbit anti-Human IL-17A
SDP

Supplier:  ABclonal Technology A27826100T

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This gene encodes a member of the IL-17 receptor family and produces IL-17A a proinflammatory cytokine secreted by activated T cells IL-17A triggers pathways that lead to the production of inflammatory molecules chemokines antimicrobial peptides and remodeling proteins It plays a critical role in host defense immune modulation and tissue repair primarily by stimulating non-hematopoietic cells and attracting myeloid cells to inflammation sites IL-17A regulates NF-kappaB and MAPK pathways enhancing the expression of IL6 COX-2 and nitric oxide production It is involved in various infectious diseases inflammatory disorders and cancer Elevated levels of IL-17A are linked to chronic diseases like rheumatoid arthritis psoriasis multiple sclerosis and lung damage in COVID-19 caused by SARS-CoV-2

Catalog No. 50-000-14174


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