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Medchemexpress LLC 4H-1-Benzopyran-3-carbonitrile, 2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(1-naphthalenyl) | 1118460-77-7 | 98.61% | 422.48 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY1091410MM/1ML

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UCPH-101 is a potent excitatory amino acid transporter subtype 1 (EAAT1) inhibitor, demonstrating an IC50 of 0.66 μM. This compound is intended for research applications only and is not suitable for patient use.

  • Inhibits EAAT1 anion currents with a KD value of 0.34±0.03 μM (Hill=1.3±0.13, n≥9).
  • Causes a small but significant decrease in total expression levels of HA-EAAT1 and HA-GLAST in cells preincubated with 100 μM UCPH-101 (p=0.048).

Catalog No. 50-003-45335


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