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Medchemexpress LLC 4H-1-Benzopyran-4-one, 6-methyl-2-(4-morpholinyl)-8-[1-(phenylamino)ethyl]- | 901398-68-3 | 99.05% | 364.44 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11118410MM/1ML

Encompass_Preferred

PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor. It is suitable for research applications, particularly in studies involving PI3Kbeta-mediated Akt phosphorylation and mTORC2-mediated Akt phosphorylation.

  • Inhibits human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue with an IC50 of 3 nM.
  • Inhibits human PI3Kbeta-mediated Akt phosphorylation at T308 residue with an IC50 of 3 nM.
  • Inhibits mTORC2-mediated Akt phosphorylation at Ser473 residue with an IC50 of 3 nM.
  • Blocks phosphorylation of PKB/Akt at concentrations of 0.1-10 μM.
  • Soluble in DMSO at 50 mg/mL.
  • Clear solution with 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline at ≥ 2.08 mg/mL.
  • Clear solution with 10% DMSO, 90% (20% SBE-β-CD in Saline) at ≥ 2.08 mg/mL.
  • Clear solution with 10% DMSO, 90% Corn Oil at ≥ 2.08 mg/mL.

Catalog No. 50-003-43853


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