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Medchemexpress LLC 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g·mol⁻¹ | C25H20F3N5O2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1017745MG

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CSF1R-IN-1 is a potent small-molecule inhibitor of the colony-stimulating factor 1 receptor (CSF1R) with a reported IC50 of 0.5 nM. The compound demonstrates good intestinal permeability in Caco-2 assays and favorable oral pharmacokinetics in mice, supporting its use for in vivo pharmacology testing in preclinical tumor models.

  • Potent CSF1R inhibition (IC50 = 0.5 nM).
  • Good intestinal permeability in Caco-2 assays.
  • Favorable oral pharmacokinetics in mice for in vivo studies.
  • High purity suitable for research applications.
  • Recommended storage as a powder at -20°C to maintain stability.

Catalog No. 50-002-45604


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