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Medchemexpress LLC 5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one | 1380392-05-1 | MFCD30489012 | 99.2% | 419.95 g/mol | C25H26ClN3O | 10MG

Supplier: Medchemexpress LLC HY12391810MG
JMS-17-2 is a potent, selective antagonist of the chemokine receptor CX3CR1 used in research to inhibit CX3CR1-mediated signaling. It shows an IC50 of 0.32 nM and has been reported to impair metastatic seeding and colonization of breast cancer cells, making it useful for in vitro pharmacology and cell-based assays.
- Potent CX3CR1 inhibition (IC50 0.32 nM).
- High reported purity (99.18%).
- Defined chemical characteristics: C25H26ClN3O, MW 419.95 g/mol.
- Solid, white to off-white appearance.
- Storage: in solvent, -80 °C up to 6 months; -20 °C up to 1 month; protect from light.
- Relevant for studies of metastatic seeding and colonization in cancer research.
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