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Medchemexpress LLC 5-(3-hydroxyphenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxamide. | 1354790-56-9 | 99.8% | 294.31 g·mol⁻¹ | C16H14N4O2 | 10MM 1ML
SDP

Supplier:  Medchemexpress LLC HY12630110MM 1ML

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DMT1 blocker 1 is a small-molecule inhibitor of the divalent metal transporter 1 (DMT1) with a reported IC50 of 0.64 μM. It inhibits intestinal non-heme iron absorption, shows efficacy in rodent models of acute iron hyperabsorption, and has high metabolic stability in rat liver microsomal incubation. The compound is provided in solid form and as a 10 mM solution in DMSO for ready use.

  • inhibits DMT1 with IC50 of 0.64 μM.
  • reduces intestinal non-heme iron absorption.
  • demonstrated efficacy in rodent models of iron hyperabsorption.
  • high metabolic stability in rat liver microsomes.
  • available as solid and as 10 mM solution in DMSO.
  • provided with certificate of analysis and safety data sheet.

Catalog No. 50-002-38758


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