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Medchemexpress LLC 5-(4-butoxy-3-chlorophenyl)-N-((2-morpholinopyridin-3-yl)methyl)nicotinamide | 1266212-81-0 | 98.0% | 480.99 | C26H29ClN4O3 | 50 MG
Supplier: Medchemexpress LLC HY10008050MG
A-887826 is a potent, selective, voltage-dependent Nav1.8 (NaV1.8) sodium channel blocker described in peer-reviewed literature. It inhibits recombinant human Nav1.8 channels with an IC50 of approximately 11 nM, is orally bioavailable in preclinical models, and attenuates neuropathic tactile allodynia. It is provided as a research-grade solid for preclinical pharmacology studies.
- Potent Nav1.8 inhibition with IC50 ~11 nM.
- Selective, voltage-dependent mechanism of action.
- Demonstrated oral bioavailability in preclinical studies.
- Reduces neuropathic tactile allodynia in animal models.
- Supplied as research-grade powder with typical purity of 98.0%.
- Chemical formula C26H29ClN4O3; molecular weight 480.99.
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