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Cayman Chemical 5 7 3 4Tetramethoxyflavon 50mg
Supplier: Cayman Chemical 4027250 MG
A flavone with diverse biological activities; selectively inhibits MRP1 over MRP2 (IC50s = 7.9 and >50 µM, respectively); inhibits LPS-induced nitric oxide (NO) release in primary mouse peritoneal macrophages from 0.03-30 µM; active against P. falciparum (IC50 = 4.06 UG/ml); is cytotoxic to B16/F10 melanoma cells at 20 µM; inhibits IL-33-induced production of CCL2 and CCL5 in primary human mast cells at 50 and 100 µM; decreases the synovial fluid levels of PGE2, IL-1β, and TNF-α in a rat model of surgically induced osteoarthritis at 100 mg/kg
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