Medchemexpress LLC 5,7,4'-Trimethoxyflavone | 5631-70-9 | 50 MG

Supplier:  Medchemexpress LLC HYN681850MG

5,7,4'-Trimethoxyflavone (MTF) can be isolated from the medicinal plant Kaempferia parviflora. It acts as a CFTR activator and induces apoptosis by increasing proteolytic activation of caspase-3 and degrading ADP-ribose polymerase (PARP) protein. This compound also exhibits antitumor activity and can be used to prevent skin aging and oxidative stress. In vitro studies have shown its ability to inhibit cell proliferation and induce apoptosis in SNU-16 cells, as well as its anti-inflammatory and anti-oxidative effects in HDFs cells.

• Isolated from the medicinal plant Kaempferia parviflora.
• Acts as a CFTR activator with an EC50 of 64 μM.
• Induces apoptosis, increases proteolytic activation of caspase-3, and degrades PARP protein.
• Exhibits antitumor activity.
• Prevents skin aging and oxidative stress.
• Demonstrated cytotoxicity in SNU-16 cells.

Catalog No. 50-004-20198