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  7. 5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific Chemicals

5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific Chemicals

Catalog Number AA4385303
Click to view available options
Quantity:
250 mg
1 g
5 g
491-80-5
C16H12O5
284.27
MFCD00006839
WUADCCWRTIWANL-UHFFFAOYSA-N
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
5280373
CHEBI:17574
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
491-80-5
C16H12O5
284.27
MFCD00006839
WUADCCWRTIWANL-UHFFFAOYSA-N
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
5280373
CHEBI:17574
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O

Description

It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Melting Point 210°C to 213°C
Quantity 1 g
Beilstein 278107
Solubility Information Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C).
Formula Weight 284.27
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 5,7-Dihydroxy-4'-methoxyisoflavone

Safety and Handling

EINECSNumber 207-744-7
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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