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5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific™

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Quantity:
250mg
1g
5g
491-80-5
C16H12O5
284.27
MFCD00006839
WUADCCWRTIWANL-UHFFFAOYSA-N
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
5280373
CHEBI:17574
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
491-80-5
C16H12O5
284.27
MFCD00006839
WUADCCWRTIWANL-UHFFFAOYSA-N
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
5280373
CHEBI:17574
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O

It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Melting Point 210°C to 213°C
Beilstein 278107
Quantity 250mg
Solubility Information Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C).
Formula Weight 284.27
Physical Form Powder
Percent Purity 98%
Chemical Name or Material 5,7-Dihydroxy-4'-methoxyisoflavone

EINECSNumber : 207-744-7

TSCA : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only