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Cayman Chemical 5 8 11-EIcosatrIynoIc AcId 1mg
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Supplier:  Cayman Chemical 902001 MG

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5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.{66} 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM.{650} At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases (ID50 = 340 µM).{66}

Catalog No. 50-289-7031


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