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Medchemexpress LLC 5,8,11-trioxa-2-azatetradecanedioic acid, 1-(4-cycloocten-1-yl) ester | 2141981-86-2 | ≥98.0% | 373.44 g/mol | C18H31NO7 | 5 MG
Supplier: Medchemexpress LLC HY1400155MG
TCO-PEG3-acid is a trans-cyclooctene-functionalized PEG3 carboxylic acid used as a click-chemistry reagent for rapid bioorthogonal conjugation. The TCO moiety undergoes inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine derivatives, enabling fast and selective labeling or linker assembly in chemical biology and bioconjugation workflows.
- Provides rapid, bioorthogonal iEDDA conjugation with tetrazine partners.
- Includes a PEG3 spacer to improve solubility and reduce steric hindrance.
- Terminal carboxylic acid enables standard coupling chemistries.
- High solubility in DMSO; ultrasonic assistance may aid dissolution.
- Stable under recommended storage conditions (for example, -20°C for extended storage).
- Suitable for labeling, linker synthesis, and bioconjugation applications.
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