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Sigma Aldrich Fine Chemicals Biosciences 5-Azacytidine, 320-67-2, MFCD00006539, 100 mg
Supplier: Sigma Aldrich Fine Chemicals Biosciences A2385100MG
Empirical Formula (Hill Notation): C8H12N4O5, Molecular Weight: 244.20, ≥98% (HPLC), Synonym: 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, 5-Azacitidine, Ladakamycin. A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes.
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