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5-Azacytidine, 98%

Catalog No. AAJ6415903
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Quantity:
1 g
5 g

Causes DNA demethylation or hemi-demethylation; a powerful mutagen | CAS: 320-67-2 | C8H12N4O5 | 244.21 g/mol

5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

Solubility
Soluble in water.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 320-67-2
Molecular Formula C8H12N4O5
Molecular Weight (g/mol) 244.21
MDL Number MFCD00006539
InChI Key NMUSYJAQQFHJEW-KVTDHHQDSA-N
Synonym 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
PubChem CID 9444
ChEBI CHEBI:2038
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
SMILES NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Specifications

Melting Point 226°C to 232°C (decomposition)
Color White
Quantity 1 g
Beilstein 620461
Merck Index 14,890
Solubility Information Soluble in water.
Formula Weight 244.2
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 5-Azacytidine
Hazard Category H302-H340-H350
Hazard Statement GHS H Statement
H340-H350-H302
May cause genetic defects.
May cause cancer.
Harmful if swallowed.
Precautionary Statement P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
EINECSNumber 206-280-2
RTECSNumber XZ3017500
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only

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