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Medchemexpress LLC 5-benzyl-2-hydroxy-3-nitrobenzaldehyde | 328565-16-8 | MFCD00852947 | ≥95.0% | 257.24 g/mol | C14H11NO4 | 100MG
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Supplier:  Medchemexpress LLC HY124817100MG

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Col003 (5-benzyl-2-hydroxy-3-nitrobenzaldehyde; CAS 328565-16-8) is a small-molecule inhibitor of heat shock protein 47 (Hsp47) that competitively binds the collagen-binding site, disrupts Hsp47-collagen interaction, and inhibits collagen secretion. It is used for research into fibrosis and collagen-processing pathways.

  • Selective Hsp47 inhibitor with reported IC50 = 1.8 μM.
  • Disrupts collagen secretion by destabilizing the collagen triple helix.
  • Suitable for fibrosis and collagen pathway studies in vitro.
  • Molecular formula C14H11NO4; molecular weight 257.24 g/mol.
  • Soluble in DMSO (50 mg/mL); in vivo solubility reported 2.5 mg/mL.
  • Storage recommendations: solid at 4°C under nitrogen; in solvent -80°C (6 months) or -20°C (1 month) under nitrogen.

Catalog No. 50-002-39544


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