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Medchemexpress LLC 5-chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol | 315698-36-3 | MFCD02330713 | >=98.0% | 354.83 g/mol | C19H19ClN4O | 5 MG
SDP

Catalog No. 5000264404
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MLS1547 is a small-molecule, G protein-biased agonist of the dopamine D2 receptor used in research to probe receptor signaling bias. It preferentially stimulates G protein-mediated signaling with micromolar potency while showing reduced β-arrestin recruitment, making it useful for studies of biased agonism and D2 receptor pharmacology.

  • Preferentially activates G protein signaling over β-arrestin pathways.
  • D2 receptor agonist activity (Ki ≈ 1.2 μM; EC50 ≈ 0.37 μM).
  • Antagonizes dopamine-stimulated β-arrestin recruitment (IC50 ≈ 9.9 μM).
  • High purity suitable for biochemical assays (≥98% HPLC).
  • Supplied in small research quantities for laboratory studies.
  • Store refrigerated at +4 °C to maintain stability.

Catalog No. 50-002-64404 Supplier Medchemexpress LLC Supplier No. HY1281215MG
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MLS1547 is a small-molecule, G protein-biased agonist of the dopamine D2 receptor used in research to probe receptor signaling bias. It preferentially stimulates G protein-mediated signaling with micromolar potency while showing reduced β-arrestin recruitment, making it useful for studies of biased agonism and D2 receptor pharmacology.

  • Preferentially activates G protein signaling over β-arrestin pathways.
  • D2 receptor agonist activity (Ki ≈ 1.2 μM; EC50 ≈ 0.37 μM).
  • Antagonizes dopamine-stimulated β-arrestin recruitment (IC50 ≈ 9.9 μM).
  • High purity suitable for biochemical assays (≥98% HPLC).
  • Supplied in small research quantities for laboratory studies.
  • Store refrigerated at +4 °C to maintain stability.

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