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Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide | 2112809-98-8 | 98.4% | 384.83 g/mol | C16H17ClN2O5S | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11743250MG

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JC-171 is a selective NLRP3 inflammasome inhibitor that reduces LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM. It is supplied as a solid and as a DMSO solution for research use, with reported high purity and defined storage recommendations.

  • Selective NLRP3 inflammasome inhibition in cell-based assays.
  • Activity: IC50 8.45 μM for inhibition of IL-1β release.
  • High reported purity: 98.41%.
  • Molecular weight 384.83 g/mol; formula C16H17ClN2O5S.
  • Available as solid quantities and as a 10 mM solution in DMSO.
  • Storage recommendations provided for powder and in-solution stability.

Catalog No. 50-002-26690


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