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Medchemexpress LLC 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl]-2-hydroxybenzamide | 212135-62-1 | 96.0% | C22H15Cl3N2O2 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13653210MG

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ZT-1a is a small-molecule, non-ATP-competitive inhibitor of STE20/SPS1-related proline-alanine-rich kinase (SPAK/STK39). It has been reported to inhibit SPAK enzymatic activity with mid-micromolar IC50 values and is used as a biochemical probe to study SPAK-dependent regulation of ion transporters.

  • Non-ATP-competitive inhibition of SPAK
  • Reported IC50 values: 44.3 μM (0.01 mM ATP), 35.0 μM (0.1 mM ATP), 46.7 μM (1 mM ATP)
  • Molecular formula: C22H15Cl3N2O2
  • Molecular weight: 445.73 g·mol⁻¹
  • Useful as a biochemical probe for studying SPAK-dependent signaling
  • Available in small research quantities for in vitro studies

Catalog No. 50-002-61216


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