5-Chlorothiophene-2-sulfonyl chloride, 97%

Description

CAS: 2766-74-7 | C4H2Cl2O2S2 | 217.08 g/mol

5-Chlorothiophene-2-sulfonyl chloride is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It is used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Not miscible in water.

Notes
Moisture Sensitive. Store at 4°C. Incomaptible with oxidizing agents and bases.

Specifications

Chemical Identifiers

• CAS: 2766-74-7
• Molecular Formula: C4H2Cl2O2S2
• Molecular Weight (g/mol): 217.08
• MDL Number: MFCD00051667
• InChI Key: SORSTNOXGOXWAO-UHFFFAOYSA-N
• Synonym: 5-chlorothiophene-2-sulfonylchloride, 5-chloro-2-thiophenesulfonyl chloride, 5-chlorothiophene-2-sulphonyl chloride, 5-chlorothiophenesulphonyl chloride, 5-chloro-2-thienylsulfonyl chloride, 5-chloro-thiophene-2-sulfonyl chloride, 5-chlorothiophenesulfonyl chloride, 5-chlorothiophen-2-sulfonyl chloride, 5-chlorothiophene-2-sulphonylchloride, 2-thiophenesulfonyl chloride, 5-chloro
• PubChem CID: 2733925
• IUPAC Name: 5-chlorothiophene-2-sulfonyl chloride
• SMILES: ClC1=CC=C(S1)S(Cl)(=O)=O

• Density: 1.623
• Boiling Point: 117°C to 120°C (14 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.586
• Quantity: 10 g
• UN Number: UN3265
• Beilstein: 130710
• Sensitivity: Moisture sensitive
• Solubility Information: Not miscible in water.
• Formula Weight: 217.09
• Percent Purity: 97%
• Chemical Name or Material: 5-Chlorothiophene-2-sulfonyl chloride

Safety and Handling

Hazard Category	H314
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: III
EINECSNumber	700-248-6
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only