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Medchemexpress LLC 5'-Deoxy-5-fluorocytidine | 66335-38-4 | 99.91% | 245.21 | 100 G
Supplier: Medchemexpress LLC HYW009538100G
5'-Deoxy-5-fluorocytidine is a cytidine analog and a metabolite of Capecitabine. It is converted by carboxylesterase in the liver and then deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil by thymidine phosphorylase in tumor tissues, exerting anti-tumor effects.
- Used in research for solid tumors such as colorectal cancer, non-small cell lung cancer, and breast cancer.
- Significantly inhibits the proliferation of chemotherapy-resistant A549 paraclone cells in vitro (at 200 μM).
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