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Medchemexpress LLC 5'-Deoxy-5-fluorocytidine (Standard) | 66335-38-4 | 99.9% | 245.21 | 1 ML
Supplier: Medchemexpress LLC HYW00953810MM/1ML
5'-Deoxy-5-fluorocytidine is a cytidine analog and a metabolite of Capecitabine. It is converted from Capecitabine by carboxylesterase in the liver. This compound is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is then converted into 5-fluorouracil by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. It is used in research for solid tumors such as colorectal cancer, non-small cell lung cancer, and breast cancer.
- Significantly inhibits the proliferation of chemotherapy-resistant A549 paraclone cells.
- Used in research for solid tumors such as colorectal cancer, non-small cell lung cancer, and breast cancer.
- Cytidine analog and metabolite of capecitabine.
- Converted to 5-fluorouracil by thymidine phosphorylase in tumor tissues.
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