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Cayman Chemical 5-Formyl-2-deoxyurIdIn 10mg
SDP

Supplier:  Cayman Chemical 4030610 MG

Encompass_Preferred

A RIPK1 inhibitor selectively binds to RIPK1 over RIPK3 (Kds 85 and 10000 nM respectively) inhibits necrosome formation and phosphorylation of RIPK1 induced by TNF-a SM-164 and Z-VAD-FMK in HT-29 cells (EC50 22.4 nM) decreases reductions in body temperature and improves survival in a mouse model of TNF-a- and Z-VAD-FMK-induced SIRS at 10 and 20 mg/kg reduces lung RIPK1 phosphorylation IL-6 and TNF-a levels and total protein content as well as decreases the number of hemorrhagic sites and congestion edema in a mouse model of short-term intratracheal NNK exposure-induced ALI

Catalog No. 50-294-2321


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