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Apexbio Technology LLC 5-hydroxypyrazine-2-carboxylic acid 34604-60-9 1g
Supplier: Apexbio Technology LLC A31241000
5-Hydroxypyrazine-2-carboxylic acid (CAS 34604-60-9) is a metabolite generated during the hepatic metabolism of the anti-tuberculosis drug pyrazinamide It is studied for its involvement in elucidating bacterial resistance mechanisms and drug metabolism pathways associated with Mycobacterium tuberculosis In vitro assays commonly utilize 5-Hydroxypyrazine-2-carboxylic acid to examine biological activity against mycobacterial enzymes related to tuberculosis pathogenesis and resistance development In enzyme inhibition studies this metabolite is employed to determine inhibition potencies characterized by IC50 measurements Based on these properties 5-Hydroxypyrazine-2-carboxylic acid holds research potential in drug discovery and resistance research for tuberculosis
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