Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000364391

Medchemexpress LLC 5-(N,N-Hexamethylene)-amiloride | 1428-95-1 | 99.14% | 311.77 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHY128067

Encompass_Preferred

5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is a derivative of amiloride, functioning as a potent Na+/H+ exchanger inhibitor. It effectively decreases intracellular pH and induces apoptosis in leukemic cells. Furthermore, it inhibits the HIV-1 Vpu virus ion channel and has been shown to suppress the replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV229E) in cultured L929 cells.

  • Potent Na+/H+ exchanger inhibitor
  • Decreases intracellular pH
  • Induces apoptosis in leukemic cells
  • Inhibits HIV-1 Vpu virus ion channel
  • Suppresses mouse hepatitis virus (MHV) replication
  • Suppresses human coronavirus 229E (HCoV229E) replication
  • Inhibits human cardiac ion channels hERG, Nav1.5, and Cav1.2
  • Exhibits microsomal stability
  • Shows mouse plasma stability and plasma protein binding
  • Displays Caco-2 cell permeability

Catalog No. 50-003-64391


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.