Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) | 1197033-19-4 | 98.6% | 899.97 | 100 MG
Supplier: Medchemexpress LLC HY148503100MG
5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer for synthesizing locked nucleic acid (LNA) analog oligonucleotides. It acts as a building block for antisense oligonucleotides (ASOs), targeting complementary RNA sequences. This compound features a 2',4'-constrained ethyl (cEt) modification, which enhances hybridization affinity, improves mismatch discrimination with RNA, and significantly increases resistance to exonuclease digestion. It mediates RNase H-dependent mRNA degradation or inhibits translation by forming stable hybrids, thereby regulating gene expression.
- Used in antisense drug development and gene therapy.
- Applicable in molecular biology techniques, including PCR and primer extension.
- Aids in gene silencing and small RNA research.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?