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Medchemexpress LLC 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) | 1197033-19-4 | 98.6% | 899.97 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14850350MG

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5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer for synthesizing locked nucleic acid (LNA) analog oligonucleotides. It serves as a building block for antisense oligonucleotides (ASOs) to target complementary RNA sequences.

  • Locks the furanose ring into an N-type conformation through 2',4'-constrained ethyl (cEt) modification
  • Enhances hybridization affinity and mismatch discrimination with RNA
  • Significantly improves the resistance of oligonucleotides to exonuclease digestion
  • Mediates RNase H-dependent mRNA degradation or inhibits translation
  • Primarily used in the development of antisense drugs, gene function research, and oligonucleotide synthesis

Catalog No. 50-003-62008


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