Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000012962

ABclonal Technology 594 Rabbit anti-Human Nectin-4
SDP

Catalog No. 5000012962
Encompass_Preferred

Nectin-4 poliovirus Receptor-like 4 (PVRL4) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily that promotes intercellular adhesion by acting as a major component of adhesion junctions The extracellular domain of Nectin-4 consists of one Ig variable region (V) and two Ig constant regions (C) which mediate binding to measles virus and adjacent cells through trans-heterophile interactions with Nectin-1 Unlike other members of the connectin family which are widely expressed in adult tissues human Nectin-4 expression is largely limited to the blastoderm Studies have shown that Nectin-4 is overexpressed in cells from a variety of human solid tumors including pancreatic breast lung and ovarian cancers The expression pattern of Nectin-4 in normal tissues is limited so NECTIN-4 can be used as a novel therapeutic target for various human tumors

Catalog No. 50-000-12962 Supplier ABclonal Technology Supplier No. A25194200T
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Nectin-4 poliovirus Receptor-like 4 (PVRL4) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily that promotes intercellular adhesion by acting as a major component of adhesion junctions The extracellular domain of Nectin-4 consists of one Ig variable region (V) and two Ig constant regions (C) which mediate binding to measles virus and adjacent cells through trans-heterophile interactions with Nectin-1 Unlike other members of the connectin family which are widely expressed in adult tissues human Nectin-4 expression is largely limited to the blastoderm Studies have shown that Nectin-4 is overexpressed in cells from a variety of human solid tumors including pancreatic breast lung and ovarian cancers The expression pattern of Nectin-4 in normal tissues is limited so NECTIN-4 can be used as a novel therapeutic target for various human tumors

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.