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Cayman Chemical 5Z 11Z 15R15HydroxyeIcosa
SDP

Supplier:  Cayman Chemical 19557250 UG

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A potent inhibitor of B-RafV600E (Kd 14 nM in an in vitro binding assay) blocks B-RafV600E dependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC50s 78 and 60 nM respectively) displays good oral bioavailability

Catalog No. 50-298-1820


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