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Medchemexpress LLC (5Z)-5-[[5-[6-(4-acetylpiperazin-1-yl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylidene]-1,3-thiazolidine-2,4-dione | 853953-65-8 | 98.5% | C21H18FN5O5S | 10MG
SDP

Supplier:  Medchemexpress LLC HY13855910MG

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GW604714X is a small-molecule inhibitor of the mitochondrial pyruvate carrier (MPC) used in research to study pyruvate transport and mitochondrial metabolism. It potently inhibits MPC (Ki <0.1 nM), selectively impairs pyruvate-supported mitochondrial respiration, and at much higher concentrations can inhibit MCT1-mediated L-lactate transport.

  • Potent MPC inhibition (Ki <0.1 nM).
  • Selectively inhibits pyruvate-supported mitochondrial respiration.
  • Secondary inhibition of monocarboxylate transporter 1 (MCT1) at higher concentrations.
  • Chemical formula C21H18FN5O5S and molecular weight 471.46.
  • Reported purity 98.49% for research use.

Catalog No. 50-002-59070


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