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Medchemexpress LLC 6-cyano-2-(1-cyclohexyl-1H-indol-4-yl)-5-((E)-3-ethoxyacryloyl)-N-methylbenzamide | 2226521-65-7 | 99.6% | 428.49 g/mol | C24H24N6O2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY10204610MG

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FM-381 is a potent covalent reversible inhibitor of Janus kinase 3 (JAK3) that targets the unique Cys909 residue. It demonstrates sub-nanomolar potency and strong selectivity versus other JAK family members, and is supplied as a high-purity research reagent for biochemical and cellular studies.

  • Potent JAK3 inhibition (IC50 127 pM)
  • High selectivity over JAK1, JAK2, and TYK2
  • High purity suitable for research applications
  • Stable powder storage at -20°C for long-term use
  • Soluble in DMSO (8.33 mg/mL) for in vitro assays

Catalog No. 50-002-47344


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