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AdipoGen 6-ECDCA
Supplier: AdipoGen AGCR13560M025
Chemical. CAS 459789-99-2. Formula C26H44O4. MW 420.6. Potent and selective FXR agonist EC50= 99nM. Induces SHP in HSCs to suppress TIMP-1 expression. Apoptosis inducer. Protects against liver fibrosis development in rat in vivo. Displays anticholeretic activity in rat in vivo. Promotes preadipocyte differentiation. Regulates adipogenesis and insulin signaling in vivo. Inhibits vascular smooth muscle cell inflammation and migration.
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