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Enzo Life Sciences 6-ECDCA (5mg). CAS: 459789-99-2
Supplier: Enzo Life Sciences BMLGR2460005
A novel derivative of cholic acid which acts as a potent and selective FXR agonist (EC50= 99nM) displaying anticholeretic activity in an in vivo rat model of cholestasis. It not only inhibits vascular smooth muscle cell inflammation and migration but also promotes adipocyte differentiation and regulates adipose cell function in vivo. Alternative name: 6-Ethylchenodeoxycholic acid, 3alpha,7alpha-Dihydroxy-6alpha-ethyl-5beta-cholan-24-oic acid, Obeticholic acid. Purity: ≥97% (TLC). Solubility: Soluble in DMSO (35mg/ml) or 100% ethanol (25mg/ml). Long Term Storage: -20°C.
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