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Medchemexpress LLC 6α-ethyl-3α,7α,23-trihydroxy-24-nor-5β-cholan-23-sulfate | 1000403-03-1 | >98.0% | 494.66 g·mol⁻1 | C25H43NaO6S | 50MG
Supplier: Medchemexpress LLC HY1243450MG
INT-767 is a synthetic dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5 (GPBAR1), used as a research reagent in preclinical studies of liver and metabolic disease. Reported activity includes mean EC50s of 30 nM (FXR) and 630 nM (TGR5); CAS 1000403-03-1; molecular formula C25H43NaO6S; molecular weight 494.66 g·mol⁻1. Typical supplier-reported purity is >98%. Material is for research use only and not for human therapeutic use.
- Dual FXR and TGR5 agonist for bile-acid signaling studies.
- Well-characterized potency: EC50 30 nM (FXR) and 630 nM (TGR5).
- High reported purity suitable for in vitro and in vivo experiments.
- Supplied as the sodium-sulfate derivative with defined molecular weight.
- Widely used in preclinical models of liver injury, steatosis, and metabolic regulation.
- For research use only; not for clinical or human use.
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