6-Fluoro-2-methylquinoline, 98+%

Description

CAS: 1128-61-6 | C10H8FN | 161.179 g/mol

Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Bronsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Brønsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.

Solubility
Soluble in Chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1128-61-6
• Molecular Formula: C10H8FN
• Molecular Weight (g/mol): 161.179
• MDL Number: MFCD00041233
• InChI Key: GPIARMSVZOEZCV-UHFFFAOYSA-N
• Synonym: 6-fluoroquinaldine, quinoline, 6-fluoro-2-methyl, 2-methyl-6-fluoroquinoline, 6-fluor-2-methylchinolin, 6-fluoro quinaldine, pubchem7579, acmc-1boyk, maybridge1_000571, 6-fluoro-2-methyl-quinoline, 6-fluoro-2-methyl quinoline
• PubChem CID: 70784
• IUPAC Name: 6-fluoro-2-methylquinoline
• SMILES: CC1=NC2=C(C=C1)C=C(C=C2)F

• Melting Point: 52°C to 56°C
• Quantity: 5 g
• Beilstein: 1281677
• Solubility Information: Soluble in Chloroform.
• Formula Weight: 161.18
• Percent Purity: ≥98%
• Chemical Name or Material: 6-Fluoro-2-methylquinoline

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	214-439-2
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only