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Medchemexpress LLC 6-hydroxy-7-methoxycoumarin | 776-86-3 | 192.17 | 5 MG
Supplier: Medchemexpress LLC HYN13655MG
Isoscopoletin is an active constituent found in Artemisia argyi leaves. It demonstrates inhibitory activity against HBV replication and exhibits anti-inflammatory effects by inhibiting the MAPK/NF-κB/STAT/AKT signaling pathway. It also significantly inhibits cell proliferation.
- Significantly inhibits cell proliferation in human CCRF-CEM leukaemia cells and multidrug-resistant subline CEM/ADR5000 cells.
- Demonstrates inhibitory activity against HBV replication.
- Exhibits anti-inflammatory effects by inhibiting the MAPK/NF-κB/STAT/AKT signaling pathway.
- Inhibits intracellular glucose consumption and lactate production in tumor cells.
- Downregulates levels of TARC, MDC, MCP-1, IL-8, and IL-1β in HaCaT cells.
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