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Medchemexpress LLC 6-Mercaptopurine hydrate | 6112-76-1 | 99.9% | 170.19 | 100 MG
Supplier: Medchemexpress LLC HY13677A100MG
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic and immunosuppressive agent.
- Purine analogue.
- Antagonist of endogenous purines.
- Induces NR4A3 transcriptional activity 1.6- to 11-fold in a dose-responsive manner.
- Leads to a dose-dependent increase in NR4A3 protein levels.
- Increases cell surface GLUT4 in both basal cells (1.8- to 3.6-fold) and insulin-stimulated cells (2.9- to 4.4-fold) over controls.
- Increases phospho-AS160 significantly in a dose-responsive manner under both basal and insulin-stimulated conditions.
- Induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain.
- Purity: 99.9%.
- Appearance: Solid.
- Color: Light yellow to yellow.
- Used as an antileukemic agent.
- Used as an immunosuppressive agent.
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