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Medchemexpress LLC 6-Methoxyflavanone | 3034-04-6 | 254.28 | 1 G
Supplier: Medchemexpress LLC HYN88521G
6-Methoxyflavanone (6-MeOF) is a flavonoid compound capable of crossing the blood-brain barrier. It acts as a positive allosteric modulator of GABAA receptors, specifically showing regulatory effects on human recombinant α1β2γ2L and α2β2γ2L GABAA receptors, with low activity on the α1β2 GABAA receptor. Additionally, it inhibits the activation of bitter receptors hTAS2R39 and hTAS2R14, exhibiting a reversible and non-overcome antagonistic effect. This compound is noted for its anti-anxiety, analgesic, and neuropathic pain relief properties.
- Flavonoid compound
- Crosses the blood-brain barrier
- Positive allosteric modulator of GABAA receptors
- Inhibits bitter receptors hTAS2R39 and hTAS2R14
- Exhibits anti-anxiety effects
- Provides analgesia
- Offers relief of neuropathic pain
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