Medchemexpress LLC 6-Methoxyflavone 50mg

Supplier:  Medchemexpress LLC HYW09762550MG

6-Methoxyflavone is an orally active methoxyflavone 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF- B dependent pathways and the activation of HO-1/NQO-1 signaling 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway and activates the PERK/EIF2a/ATF4/CHOP pathway in HeLa cells 6-Methoxyflavone acts as a Flumazenil (HY-B0009)-insensitive positive allosteric modulator at human recombinant 1 2 2L and 2 2 2L GABA receptors 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression 6-Methoxyflavone can be used for the study of cancer inflammation and neurological diseases[1][2][3][4][5][6][7][8]

Catalog No. 50-002-04568