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Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
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Supplier:  Medchemexpress LLC HY1876210MM/1ML

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6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.

  • Nucleoside analogue
  • Can be incorporated into de novo-synthesized telomeres by telomerase
  • Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
  • Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
  • Increases telomere dysfunction in tumor cells in vivo
  • Appearance: Solid
  • Color: White to yellow

Catalog No. 50-003-88247


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