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Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 100 MG
Supplier: Medchemexpress LLC HY18762100MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death in most tested cancer cell lines and decreases tumor growth rate in mouse xenograft models, increasing telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Induces rapid cell death in cancer cell lines
- Decreases tumor growth rate in mouse xenograft models
- Increases telomere dysfunction in tumor cells in vivo
- DNA/RNA synthesis inhibitor
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