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ABclonal Technology 647 Rabbit anti-Human TrkA
SDP

Supplier:  ABclonal Technology A23974100T

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This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family This kinase is a membrane-bound receptor that upon neurotrophin binding phosphorylates itself and members of the MAPK pathway The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes Mutations in this gene have been associated with congenital insensitivity to pain anhidrosis self-mutilating behavior mental retardation and cancer Alternate transcriptional splice variants of this gene have been found but only three have been characterized to date

Catalog No. 50-000-08277


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