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Cayman Chemical 6aMethylprednIsoLN 21hemI 50mg

Supplier: Cayman Chemical 3574250 MG

An inhibitor of p38a MAPK (Ki 0 5 nM) selective for p38a over p38Y p38 JNK1 JNK2 and JNK3 (Kis 2600 4100 11480 39 and 61 nM respectively) and is greater than 1000-fold selective over a panel of 36 additional kinases but also inhibits p38B (Ki 3 6 nM) inhibits LPS-induced production of TNF-a and IL-1B in isolated human whole blood (IC50s 3 and 7 nM respectively)
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