Cayman Chemical 6Chloro3IndolylDGlucur 100mg

Supplier:  Cayman Chemical 30131100 MG

An inhibitor of Plk1 (IC50 2 nM) selective for Plk1 over Plk2 and Plk3 (IC50s 10000 nM for both) inhibits proliferation of A2780 cells (IC50 42 nM) halts the cell cycle at the G2/M phase in A2780 cells at 20-200 nmol/L and induces apoptosis reduces tumor growth in an HCT116 mouse xenograft model at 60 mg/kg once per day induces tumor regression in an HT-29 mouse xenograft model at 45 mg/kg in combination with CPT11

Catalog No. 50-298-8618